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Hon-Man Lee

  • Of Counsel
  • New York
Hon-Man Lee is Of Counsel in the Life Science Practice Group at Pearl Cohen’s New York office. He has extensive post-doctoral training in the field of immunology. His practice is focused on U.S. and worldwide patent procurement in the life science and biotechnology areas.

BIOGRAPHY

Hon-Man Lee is Of Counsel in the Life Science Practice Group at Pearl Cohen’s New York office. His practice focuses on patent procurement in the life science and biotechnology areas. Hon-Man is experienced in patent drafting, worldwide patent prosecution, and infringement and validity opinions. His technical background includes immunology, antibody and vaccine technology, molecular biology, viral vectors and cancer research.

Before earning his law degree, Hon-Man conducted post-doctoral research at the Naval Medical Research Institute in Maryland and Baylor College of Medicine in Houston, focusing on immune T cell co-stimulation and immune response in a mouse prostate cancer model.

Prior to joining Pearl Cohen, Hon-Man worked in IP boutique firms in Washington, D.C. and New York.

Publications:

Legal Publications

  • Hon-Man Lee, An Original Grant Patent System Coming To Hong Kong, in Biotechnology in Hong Kong 297-304 (Albert Wai-Kit Chan ed., United States-CN Intellectual Property Institute Inc. 2015). 
  • Albert Wai-Kit Chan, Alice Yuen-Ting Wong, Hon-Man Lee, A Patent Perspective On US Stem Cell Research.  NATURE BIOTECHNOLOGY 32:633-637, 2014
  • Hon-Man Lee, Lauren Korshalla, Albert Wai-Kit Chan, Reasonably Withheld Consent In License Agreements.  INTELLECTUAL PROPERTY LITIGATION, AMERICAN BAR ASSOCIATION 22:16, 2010

Scientific Publications

  • Nasu Y, Bangma CH, Hull GW, Yang G, Wang J, Shimura S, McCurdy MA, Ebara S, Lee HM, Timme TL, Thompson TC., Combination Gene Therapy With Adenoviral Vector-Mediated HSV-tk+GCV And IL-12 In An Orthotopic Mouse Model For Prostate Cancer.  PROSTATE CANCER PROSTATIC DIS. 4:44-55, 2001
  • Shaker MR, Yang G, Timme TL, Park SH, Kadmon D, Ren C, Ji X, Lee HM, Sehgal I, Anzano M, Sporn MB, Thompson TC., Dietary 4-HPR Suppresses The Development Of Bone Metastasis In Vivo In A Mouse Model Of Prostate Cancer Progression.  CLIN. EXP. METASTASIS 18:429-438, 2000
  • Hull GW, McCurdy MA, Nasu Y, Bangma CH, Yang G, Shimura S, Lee HM, Wang J, Albani J, Ebara S, Sato T, Timme TL, Thompson TC., Prostate Cancer Gene Therapy: Comparison Of Adenovirus-Mediated Expression Of Interleukin 12 With Interleukin 12 Plus B7-1 For In Situ Gene Therapy And Gene-Modified, Cell-Based Vaccines.  CLIN. CANCER RES. 6:4101-4109, 2000
  • Lee HM, Timme TL, Thompson TC., Resistance To Lysis By Cytotoxic T Cells: A Dominant Effect In Metastatic Mouse Prostate Cancer Cells.  CANCER RES. 60:1927-1933, 2000
  • Nasu Y, Bangma CH, Hull GW, Lee HM, Hu J, Wang J, McCurdy MA, Shimura S, Yang G, Timme TL, Thompson TC., Adenovirus-Mediated Interleukin-12 Gene Therapy For Prostate Cancer: Suppression Of Orthotopic Tumor Growth And Pre-Established Lung Metastases In An Orthotopic Model.  GENE THER. 6:338-349, 1999
  • Adler HL, Lee HM, McCurdy MA, Herman JR, Timme TL, Scardino PT, and Thompson TC., Advenovirus-Mediated Herpes Simplex Virus-Thymidine Kinase Gene Therapy In Men With Radiorecurrent Prostate Cancer Leads To Stimulation Of The Immune System And Increases In Circulating Cytokines.  Abstract in the First Annual Meeting of The American Society of Gene Therapy, 1998)
  • Nasu Y, Bangma CH, Hull GW, Lee HM, Hu J, Wang J, McCurdy MA, Shimura S, Yang G, Timme TL, and Thompson TC., Experimental Gene Therapy For Prostate Cancer: Treatment Of Mouse Prostate Cancer With Adenovirus Mediated Interleukin-12 Gene Transduction Alone And In Combination With Herpes Simplex Virus Thymidine Kinase Gene Transduction And Ganciclovir Therapy.  Abstract in the American Urologic Association Annual Meeting, 1998
  • Wiest DL, Ashe JM, Howcroft TK, Lee HM, Kemper DM, Negishi I, Singer DS, Singer A, Abe R., A Spontaneously Arising Mutation In The DLAARN Motif Of Murine ZAP-70 Abrogates Kinase Activity And Arrests Thymocyte Development.  IMMUNITY 6:663-671, 1997
  • Rich S, Van Nood N, Lee HM., Role Of Alpha 5 Beta 1 Integrin In TGF-Beta 1-Costimulated CD8+ T Cell Growth And Apoptosis.  J. IMMUNOL. 157:2916-2923, 1996
  • Rich S, Seelig M, Lee HM, Lin J., Transforming Growth Factor Beta 1 Costimulated Growth And Regulatory Function Of Staphylococcal Enterotoxin B-Responsive CD8+ T Cells.  J. IMMUNOL. 155:609-618, 1995
  • Lee HM, Rich S., Differential Activation Of CD8+ T Cells By Transforming Growth Factor-Beta 1.  J. IMMUNOL. 151:668-677, 1993
  • Stein PL, Lee HM, Rich S, Soriano P., pp59Fyn Mutant Mice Display Differential Signaling In Thymocytes And Peripheral T Cells.  CELL 70:741-750, 1992
  • Lee HM, Rich S., Co-Stimulation of T Cell Proliferation By Transforming Growth Factor-Beta 1.  J. IMMUNOL. 147:1127-1133, 1991